N-mono(alkoxymethyl) phenobarbitals, process therefor and therap

Details N-mono(alkoxymethyl) phenobarbitals, process therefor and therap N-mono(alkoxymethyl) phenobarbitals, process therefor and therap

1974-01-18

1976-04-06

Narcavage, Joseph A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424254, C07D23962

Patent

active

039488969

ABSTRACT:
N-mono(alkoxymethyl)phenobarbitals wherein the alkoxy group has 1 to 4 carbon atoms are disclosed. The compounds are prepared by reacting the dialkali metal salt of thiophenobarbital with chloromethyl alkyl ether followed by treating the resultant N,S-bis(alkoxymethyl)thiophenobarbital with an oxidizing agent. The compounds are useful as anticonvulsant agents.

REFERENCES:
samour et al., J. of Medicinal Chemistry, 1971, Vol. 14, No. 3, pp. 187-193.

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