N-methyl-2-(3-pyridyl)-tetrahydrothio-pyran-2-carbothioamide 1-o

Details N-methyl-2-(3-pyridyl)-tetrahydrothio-pyran-2-carbothioamide 1-o N-methyl-2-(3-pyridyl)-tetrahydrothio-pyran-2-carbothioamide 1-o

1993-02-04

1995-06-20

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514314, A61K 3144

Patent

active

054261171

ABSTRACT:
Application of N-Methyl-2-(3-pyridyl)tetrahydrothiopyran-2-carbothioamide 1-oxide, in the form of a racemic mixture of the 1S,2S and 1R,2R isomers or in the form of the 1R,2R isomer, to the preparation of a medicinal product intended for the treatment of coronary insufficiency.

REFERENCES:
patent: 4568682 (1986-02-01), Aloup et al.
patent: 4751234 (1988-06-01), Aloup et al.
"RP 49356 is a Potent Opener of ATP-Modulated Potassium Channels in Cardiac Myocytes", Br. J. Pharmacol., vol. 95, Suppl., 1988, p. 814P, D. Escande et al.
European Search Report dated Jul. 10, 1990, FR 8914272, FA 433968 "Potassium Channel Operners Act Through an Activation of ATP-sensitive K+-ATP Channels in Cardiac Myocytes", Escande et al., Pflugers Arch. Eur. J. Physiol vol. 414, No. 6, Sep. 1989, pp. 669-675.
"The potassium channel opener RP 49356 modifies the ATP-sensitivity of K+-ATP channels in Cardiac Myocytes", Pflugers Arch. Eur. J. Physiol., vol. 414, Suppl. 1, 1989, p. 175, Springer Verlag, D. Thuringer, et al.
"Effects of Ca2+ antagonists of K+-channel activators on K+-induced contractions in the rat aorta", Lawson et al., J. Auton. Pharmac., vol. 9, No. 5, Oct. 1989, pp. 329-336.

Affiliated with

Also associated with

Rating

N-methyl-2-(3-pyridyl)-tetrahydrothio-pyran-2-carbothioamide 1-o does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-methyl-2-(3-pyridyl)-tetrahydrothio-pyran-2-carbothioamide 1-o, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-methyl-2-(3-pyridyl)-tetrahydrothio-pyran-2-carbothioamide 1-o will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1844330