N-hydroxysuccinimide monohydrate

Details N-hydroxysuccinimide monohydrate N-hydroxysuccinimide monohydrate

1994-06-16

1996-02-20

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548545, C07D20746

Patent

active

054930316

ABSTRACT:
N-hydroxysuccinimide monohydrate is precipitated from an aqueous solution of N-hydroxysuccinimide. N-hydroxysuccinimide monohydrate is a new compound that can be used to produce anhydrous N-hydroxysuccinimide which is substantially pure. It can also be used as a substitute for N-hydroxysuccinimide when the presence of water is not detrimental.

REFERENCES:
patent: 2816111 (1957-12-01), Wegler et al.
G. W. Anderson et al, "The Use of Esters of N-Hydroxysuccinimide in Peptide Synthesis", J. Am. Chem. Soc., 86, pp. 1838-1842, (1963).
Kirk-Othmer Encyclopedia of Chemical Technology, 2nd ed. (1965), vol. 6, p. 506.
CRC Handbook of Chemistry and Physics, 65th ed. (1984), pp. C-669 thru C-704.
104654y, "Simple synthesis of N-hydroxysuccinimide", Chemical Abstracts, (1967), p. 977.

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