N-heterocyclyl hydrazides as neurotrophic agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S279100

Reexamination Certificate

active

07087628

ABSTRACT:
This invention relates to a series of N-heterocyclyl hydrazides of Formula I,and pharmaceutical compositions containing them. The compounds of the invention have neurotrophic activity and are useful in the treatment and prevention of neuronal disorders such as Parkinson's disease, Alzheimer's disease, stroke, multiple sclerosis, amyotrophic lateral sclerosis diabetic neuropathy and Bell's palsy.

REFERENCES:
patent: 4665173 (1987-05-01), Klayman et al.
patent: 4694004 (1987-09-01), Nakaguti et al.
patent: 6271247 (2001-08-01), Monge Vega et al.
patent: 6555542 (2003-04-01), O'Connor et al.
patent: WO 01 04090 (2001-01-01), None
patent: WO 01 04091 (2001-01-01), None
PCT International Search Report dated Dec. 17, 2002.

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