N-heterocyclic-N-(4-piperidinyl) amides and pharmaceutical compo

Details N-heterocyclic-N-(4-piperidinyl) amides and pharmaceutical compo N-heterocyclic-N-(4-piperidinyl) amides and pharmaceutical compo

1988-12-09

1990-03-27

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514256, 514269, 514272, 514274, 514275, 514318, 544336, 544408, 544409, 544332, 544311, 544312, 544316, 544317, 544319, 544320, 544321, 544327, 544329, 544405, 546193, 546194, A61K 31435, A61K 31495, C07D24102, C07D21302

Patent

active

049121090

ABSTRACT:
This invention pertains to novel substituted N-heterocyclic-N-(4-piperidinyl)amides useful as analgesics and antagonists of opiods, wherein the compounds have the general formula: ##STR1## including optically active isomeric forms, and the pharmaceutically acceptable acid addition salts thereof, wherein:

REFERENCES:
patent: 4157393 (1979-06-01), Sanczuk et al.
patent: 4546105 (1985-10-01), Effland et al.
patent: 4584303 (1986-04-01), Huang et al.
patent: 4788198 (1988-11-01), Grozinger et al.
Studies on Potent Analgesics, Youcheng et al., 3/81, 12 page Article (Acta Pharmaceutica Sinica) vol. XVI, No. 3. S. Grossmann et al., Pyridin-Analoga Des Fentanyls, 1978, 6 page Article, (Arch. Pharm. Weinheim).
Janssens et al., New Antihistiminic N-Heterocyclic 4-Piperidiamines 1985, 5 pages (J. Med. Chem) vol. 28, No. 12, pp. 1925-1947.
Youcheng et al., Structural Modification of 4-N-Propionyl Group, etc. 1983, 7 pages (Yaoxue Xuebo 18(8) 591-6.

Affiliated with

Also associated with

Rating

N-heterocyclic-N-(4-piperidinyl) amides and pharmaceutical compo does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-heterocyclic-N-(4-piperidinyl) amides and pharmaceutical compo, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-heterocyclic-N-(4-piperidinyl) amides and pharmaceutical compo will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1651238