N-heterocyclic inhibitors of TNF-alpha expression

Details N-heterocyclic inhibitors of TNF-alpha expression N-heterocyclic inhibitors of TNF-alpha expression

2007-07-16

2011-10-25

Rao, Deepak (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S256000, C514S274000, C514S275000, C540S575000, C544S317000, C544S323000, C544S324000, C544S326000, C544S328000, C544S329000

Reexamination Certificate

active

08044040

ABSTRACT:
N-heterocyclic compounds that block cytokine production via inhibition of p38 kinase are disclosed. In one embodiment, compounds of the present invention are represented by Formula (I):Methods of production, pharmaceutical compositions and methods of treating conditions associated with inappropriate p38 kinase activity or TNF-α expression utilizing compounds of the present invention are also disclosed.

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