N-heterocyclic amides

Details N-heterocyclic amides N-heterocyclic amides

1988-10-05

1991-02-05

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

544391, 546247, 540492, C07D21116, C07D24104, C07D24308, C07D25702, C07D25900

Patent

active

049906143

ABSTRACT:
A compound of the formula: ##STR1## wherein ##STR2## represents a cyclic amino group, A represents a methylene group or a carbonyl group, m represents an integer of 1 to 3, n represents an integer of 0 to 4 and p represents an integer of 1 to 2, or a salt thereof, which has glutamate receptor inhibiting activity is provided.

REFERENCES:
N. Kawai, 8th Conference en Neurobiologie, Nov. 25, 1983, Gif, France, Lecture Summaries, p. 10.
N. Kawai, A. Miwa, T. Abe, Advances in Biological Psycopharmacology, 37, 221-227 (1983).
T. Abe, N. Kawai, A. Miwa, J. Physiol., 339, 243-252 (1983).
N. Kawai, A. Miwa, T. Abe, Biomed. Res. 3 353-355 (1982).
N. Kawai, S. Yamagishi, M. Saito, K. Furuya, Brain Res. 278 346-349 (1983).
Chemical Abstracts, vol. 105, No. 21, Nov. 24, 1986, p. 227, Abstract No. 186106d, Columbus, Ohio, E. V. Grishin, "Structure-Functional Characterization of Argiopine an Ion Channel Blocker from the Venom of the Spider . . . ".
N. Kawai, A., Miwa, T. Abe, Brain Res. 247, 169-171, (1982).
N. Kawai, A. Miwa, M. Saito, M. Yoshioka, Microelectrophoretic Investigations of Mammalian Central Transmitters, Aug. 25, 1983, Camberra, Australia, Lecture Summaries, p. 4.
N. Kawai, A. Miwa, M. Saito, M. Yoshioka, 29th Congress of the International Union of Physiological Sciences, Aug. 29, 1983, Sydney, Australia, Lecture Summaries p. 89.

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