N-Heterocyclic alkyl-N'-thiadiazolyl, thiazolyl and isothiazolyl

Details N-Heterocyclic alkyl-N'-thiadiazolyl, thiazolyl and isothiazolyl N-Heterocyclic alkyl-N'-thiadiazolyl, thiazolyl and isothiazolyl

1980-12-11

1983-06-14

Ford, John M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

424269, 424272, 424273R, 548136, 548138, 548142, 548182, 548183, 548184, 548185, 548186, 548187, 548189, 548193, 548198, 548202, 548203, 548204, 548205, 548213, 548214, A61K 31425, A61K 31415, A61K 3142, A61K 3141, C07D40312, C07D41312, C07D41712

Patent

active

043883192

ABSTRACT:
The compounds are N,N'-substituted thioureas, ureas and guanidines which are H-2 histamine receptor inhibitors. A compound of this invention is N-cyano-N'-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]-N"-[2-(2-thiazolyl methylthio)ethyl]guanidine.

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patent: 3749728 (1973-07-01), Loev
patent: 3770755 (1973-11-01), Hutton et al.
patent: 3781278 (1973-12-01), Siegrist et al.
patent: 3821229 (1974-06-01), Maulding
patent: 3868457 (1975-02-01), Black et al.
patent: 4013659 (1977-03-01), Durant et al.
patent: 4154838 (1979-05-01), Durant et al.
patent: 4156727 (1979-05-01), Durant et al.

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