N-heteroaryl-purin-6-amines, and pharmaceutical compositions and

Details N-heteroaryl-purin-6-amines, and pharmaceutical compositions and N-heteroaryl-purin-6-amines, and pharmaceutical compositions and

1991-05-06

1992-10-13

Rivers, Diana G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 44, 536 24, 536 26, C07H 19167, A61K 3170

Patent

active

051550989

ABSTRACT:
This invention relates to a N-heteroaryl-purin-6-amine of the formula ##STR1## where R.sub.1 is hydrogen, lower alkyl, and arylloweralkyl; R.sub.2 and R.sub.3 are independently hydrogen, lower alkyl or R.sub.2 and R.sub.3 taken together are aryl; R.sub.4 and R.sub.5 are independently hydrogen, lower alkyl, or R.sub.4 and R.sub.5 taken together are aryl; R.sub.6 is hydrogen, lower alkyl, aryl, arylloweralkyl, ##STR2## where R.sub.2, R.sub.3, R.sub.4 and R.sub.5 are as defined above, and the pharmaceutically acceptable acid addition salts thereof and where applicable the geometric and optical isomers and racemic mixtures thereof. The compounds of this invention display utility as analgesic and anitconvulsant agents.

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