N-halochitosans, their preparation and uses

Details N-halochitosans, their preparation and uses N-halochitosans, their preparation and uses

1993-02-24

1994-11-08

Collins, John W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 62, 536 20, 536 552, 536122, A61K 3173, A61K 3170, C07H 506, C08B 3708

Patent

active

053627172

ABSTRACT:
N-Halochitosans which are terpolymers containing 1 to 35% of 2-deoxy-2-acetaminodoglucose monomeric units, 1 to 90% of 2-deoxy-2-haloaminoglucose monomeric units, and 8-98% of 2-deoxy-2-haloaminoglucose monomeric units wherein the halogen is chlorine or bromine and their preparation is disclosed. The preferred preparation is by treatment of an aqueous solution of a chitosan salt with a halogenating agent.

REFERENCES:
patent: 4931551 (1990-06-01), Albisetti et al.
Comprehensive Organic Chemistry, Edited by I. O. Sutherland, Pergamon Press, vol. 2, pp. 40-41.
Y. Shigeno et al., "Journal of Applied Polymer Science" vol. 25 731-738 (1980).
T. Uragami et al., "Makromol. Chem., Rapid Commun.", vol. 4 pp. 99(1983).

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