N-Haloalkyl nor apomorphines and method of inactivating dopamine

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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546 75, 546 2, 546 3, 546 13, 424245, 424254, 544299, A61K 3147, C07D22118

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active

043539122

ABSTRACT:
N-substituted haloalkyl apomorphines of the formula ##STR1## wherein R.sub.1 is hydrogen or R.sub.2 O; R.sub.2 is hydrogen, acyl, lower alkyl or ##STR2## R.sub.3 and R.sub.4 are lower alkyl; and X is halogen; and their acid addition salts. Representative compounds have neuroleptic properties.

REFERENCES:
patent: 3717639 (1973-02-01), Neumeyer
patent: 3717643 (1973-02-01), Archer
patent: 3852452 (1974-12-01), Bruderlein et al.

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