N-formylation of amino carboxylic compounds with formamide

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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562450, 562571, 562575, C07C 9900

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047897570

ABSTRACT:
The amine nitrogen of an amino carboxylic acid is formylated by reacting the amino carboxylic acid with formamide.

REFERENCES:
Takatori, Chem. Abst., vol. 104, #58775 (1986).
Meisser et al, Chem. Abst., vol. 105, #190686k (1986).
Vilvala, Chem. Abst., vol. 89, #163,231c (1978).
Gensler et al.; J. Org. Chem.; "Cinnamic Acids from Tetrahydroisoquinoline Carboxylic Acids"; vol. 21, pp. 336, 1956.
King et al.; J. Chem. Soc.; "Synthesis from Phthalimido-Acids"; p. 880, 1957.
Sheehan et al.; J. Am. Chem. Soc.; "The Use of N-Formylamino Acids in Peptide Synthesis"; vol. 80, p. 1154, 1958.

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