N-Formyl leurosine derivatives in a dosage form effective for tr

Details N-Formyl leurosine derivatives in a dosage form effective for tr N-Formyl leurosine derivatives in a dosage form effective for tr

1975-02-05

1981-07-21

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424262, C07D51904, A61K 31475

Patent

active

042798167

ABSTRACT:
New leurosine derivatives of the general formula (1), ##STR1## wherein R stands for hydrogen or formyl, or pharmaceutically acceptable acid addition salts thereof were prepared by oxidizing leurosine or an acid addition salt thereof, optionally formylating the thus-obtained product and then separating, and, if desired, converting any of the free bases into its acid addition salt.

REFERENCES:
patent: 3387001 (1968-06-01), Hargrove et al.
"Cancer Chemotherapy Reports," vol. 1, pp. 10-13 (1959).

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