N-Formyl and N-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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260239A, A61K 31395, C07D20504

Patent

active

045059071

ABSTRACT:
N-Formyl and N-hydroxymethyl-3-phenoxy-1-azetidinecarboxamides having the formula: ##STR1## wherein R is selected from formyl and hydroxymethyl and R.sup.1 is selected from hydrogen, fluoro, loweralkyl, loweralkoxy, trifluoromethyl, acetyl, N-formylcarboxamido or N-hydroxymethylcarboxamido having antidepressant activity are disclosed.

REFERENCES:
patent: 3823006 (1974-07-01), Lorenz et al.
patent: 4031221 (1977-06-01), Helsley et al.
patent: 4226861 (1981-10-01), Cale, Jr.
patent: 4379151 (1983-04-01), Cale, Jr.
March, ed., Advanced Organic Chemistry, 2nd ed., pp. 382-385, (1977), New York McGraw-Hill.

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