N-disubstituted aminoethyl esters of 11-methoxy-raubasinic acid

Details N-disubstituted aminoethyl esters of 11-methoxy-raubasinic acid N-disubstituted aminoethyl esters of 11-methoxy-raubasinic acid

1974-07-22

1977-06-14

Todd, G. Thomas

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260268PC, 26029353, 424255, 424250, 424267, C07D49122

Patent

active

040296598

ABSTRACT:
N-disubstituted aminoethyl esters of 11-methoxy-raubasinic acid of the formula : ##STR1## in which R is an alkyl group containing up to 4 carbon atoms or the two R groups, together with the nitrogen atom to which they are attached, form a morpholinyl, piperidinyl, piperazinyl or pyrrolidinyl group, and their physiologically acceptable acid addition salts. The process for the preparation of an N-disubstituted aminoethyl ester of 11-methoxy-raubasinic acid of the formula specified hereinabove, which comprises esterifying 11-methoxy-raubasinic acid with a substituted aminoethyl halide of the formula: ##STR2## in which X is a halogen atom and R has the meaning specified in claim 1.

REFERENCES:
patent: 3072664 (1963-01-01), Salkin
patent: 3104243 (1963-09-01), Gillo

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