(-)-N"-cyano-N-3-pyridyl-N'-1,2,2-trimethylpropylguanidine

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

546306, C07D21102, A61K 3144

Patent

active

052644456

ABSTRACT:
This compound provides the compound (-)-N"-cyano-N-3-pyridyl-N'-1,2,2-trimethylpropylguanidine, its salts and pharmaceutical formulations, and its method of use for opening potassium channels in mammals.

REFERENCES:
patent: 4057636 (1977-11-01), Petersen et al.
FASEB Journal, 3(3), A435 (1989) (Abstract 1214).
Peterson et al., J. Med. Chem., 21 (8), 773 (1978).
Westin et al., Drugs, 36 (Supp. 7), 10 (1988).

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