N-cinnamylcarbamic acid esters

Details N-cinnamylcarbamic acid esters N-cinnamylcarbamic acid esters

1973-06-04

1977-03-29

Patten, James A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260240R, 260240A, 260243B, 2602472A, 260268C, 26029376, 260307A, 26032643, 260348R, 260348A, 260349, 260465D, 260465E, 260470, 260471R, 260479R, 260553R, 260562A, 2605707, 260515R, 260600R, 424246, 42424854, 424267, 424272, 424274, 424309, 424319, 424322, 424330, C07C12506

Patent

active

040149200

ABSTRACT:
Amines of the formula ##SPC1##
Wherein R.sub.1 is lower alkyl, lower alkoxy or amino, R.sub.2 is hydrogen or lower alkyl, R.sub.3 is hydrogen, lower alkyl, carboxyl or lower alkoxycarbonyl, R.sub.4 is hydrogen or lower alkyl, R.sub.5 is lower alkyl, aryl-lower alkyl or optionally functionally modified carboxy-lower alkyl and R.sub.6 denotes halogen, trifluoromethyl, lower alkyl, lower alkenyl, lower alkoxy, lower alkenyloxy, nitro, lower alkoxymethyl, carbamoyl, N-lower alkylcarbamoyl, nitrile, lower alkinyloxy or hydrogen, and their salts block cardiac and vascular .beta.-receptors the are useful in the treatment of arrhythenias and angina pectoris and as intermediates for, especially for pharmaceutically active substances.

REFERENCES:
patent: 3712927 (1973-01-01), Howe et al.
patent: 3864398 (1975-02-01), Suzuki et al.

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