N-chloro-amino acid derivatives activity

Details N-chloro-amino acid derivatives activity N-chloro-amino acid derivatives activity

1974-06-14

1976-06-29

Weinberger, Lorraine A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260468H, 260468J, 260557R, 260561A, 424305, 424307, 424311, 424320, C07D10110

Patent

active

039667960

ABSTRACT:
There is provided, a novel class of compounds exhibiting antibacterial activity, said compounds having the formula: ##EQU1## wherein X and Y each represent a member which may be the same or different selected from the group consisting of H and Cl with the priviso that X and Y cannot represent H simultaneously; R.sub.1 and R.sub.2 each represent a member which may be the same or different selected from the group consisting of an n- or branched alkyl group of from 1 to 20 carbon atoms, an aryl group (phenyl, naphthyl, etc.) and a ##EQU2## (CH.sub.2).sub.n group, wherein n represents an integer of from 2 - 5; and Z represents a member selected from the group consisting of an --OR.sub.3 group, a a ##EQU3## wherein R.sub.4 and R.sub.5 each represent a member which may be the same or different selected from the group consisting of H and an alkyl group of from 1 - 3 carbon atoms, wherein R.sub.6 and R.sub.7 each represent a member which may be the same or different selected from the group consisting of R.sub.1, R.sub.2, or H when X is not Cl or R.sub.1 and R.sub.2 when X is Cl, wherein R.sub.1 and R.sub.2 are defined above, wherein X is as defined above, and wherein R.sub.3 in each case represents a member selected from the group consisting of an n- or branched alkyl group of from 2 - 20 carbon atoms, a --OCH.sub.2 CH.sub.2 (OCH.sub.2 CH.sub.2).sub.n --OR.sub.1 group, wherein R.sub.1 is defined as above and n represents an integer of from 1 - 11, a
Group, wherein W represents a member selected from the group consisting of H, an n- or branched alkyl group of from 1 - 20 carbon atoms, a halogen atom, (Cl, Br, I), an --OR.sub.8 group, and a ##EQU4## group, wherein R.sub.4 and R.sub.5 are as defined above and R.sub.8 represents a member selcted from the group consisting of H and R.sub.1, wherein R.sub.1 is as defined above, and --CH.sub.2 CH.sub.2 --(OCH.sub.2 CH.sub.2).sub.n -- ##SPC1##
Group, wherein n represens an integer of from 1 - 20 and R.sub.1 is as defined above,

REFERENCES:
patent: 3530162 (1970-09-01), Fuchs

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