Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1982-10-21
1984-06-26
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
2601125R, 424274, 548518, A61K 3700, C07C10352
Patent
active
044565941
ABSTRACT:
Certain N-carboxyalkyl prolyl-containing tripeptides have been prepared and found to improve kidney function. A species of the group of new compounds is N-(2-carboxyethyl)-L-prolyl-L-alanyl-L-proline which has diuretic activity and increases renal blood flow. The compounds are prepared by chemical reactions which couple an amino acid with a dipeptide.
REFERENCES:
patent: 4299769 (1981-11-01), McEvoy et al.
patent: 4342689 (1982-08-01), McEvoy et al.
Chem. Abstr. vol. 53, 21693h.
Edgerton William H.
Foggio Richard D.
Lourie Alan D.
Phillips Delbert R.
SmithKline Beckman Corporation
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