N-carbobenzyloxy (N-CBZ)-deprotecting enzyme and uses therefor

Details N-carbobenzyloxy (N-CBZ)-deprotecting enzyme and uses therefor N-carbobenzyloxy (N-CBZ)-deprotecting enzyme and uses therefor

2006-10-10

2006-10-10

Swope, Sheridan (Department: 1656)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S195000

Reexamination Certificate

active

07119188

ABSTRACT:
This invention relates to isolated or recombinant N-carbobenzyloxy-deprotecting enzyme polypeptides, and variants and fragments thereof, that catalyze the removal of carbobenzyloxy from carbobenzyloxy-protected amino acids and alcohols. Also related are isolated nucleic acids encoding N-carbobenzyloxy-deprotecting enzyme polypeptides, and variants, and fragments thereof, as well as vectors and host cells comprising these nucleic acids. The invention also relates to methods of obtaining isolated nucleic acids, polypeptides, and antibodies, and methods of using the polypeptides in various reactions for industrial or pharmaceutical applications.

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