N-carbacycle monosubstituted indolocarbazoles as protein...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S231200, C514S232800, C514S359000, C544S142000, C548S416000, C548S255000

Reexamination Certificate

active

10496505

ABSTRACT:
This invention relates to N-carbacycle monosubstituted indolocarbazole compounds. Furthermore, this invention relates to medicaments comprising N-carbacycle monosubstituted indolocarbazoles compounds and the use of such compounds for treating non-insulin dependent diabetes mellitus, acute stroke and other neurotraumatic injuries, for treating diabetes mellitus, as a chemotherapeutic for the treatment of various malignant diseases, for treating diseases caused by malfunctioning of specific signaling pathways, and for treating neurodegenerative diseases such as for example Alzheimer's disease.

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patent: 9933836 (1999-07-01), None
patent: 001699 (2000-01-01), None
McCombie, et al. “Indolocarbazoles. I. Total Synthesis and Protein Kinase Inhibiting Characteristics of Compounds Related to K-252c” Bioorganic and Medicinal Chemistry Letters, vol. 3(8), pp. 1537-1542 (1993).

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