N-but-3-enyl norbuprenorphine and its use as analgesic

Details N-but-3-enyl norbuprenorphine and its use as analgesic N-but-3-enyl norbuprenorphine and its use as analgesic

2006-10-24

2006-10-24

Richter, Johann (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S039000

Reexamination Certificate

active

07125884

ABSTRACT:
The present invention provides compound having the structure: and pharmaceutically acceptable salts or derivatives thereof, as well as compositions including such compounds. The invention also provides methods of (1) preventing pain, (2) treating pain, (3) inducing sedation, (4) treating opiate addiction, (5) treating opiate withdrawal (abstinence syndrome) and/or (6) treating cough in a patient in need thereof by administering a compound or composition of the invention.

REFERENCES:
patent: 3285914 (1966-11-01), Gordon et al.
patent: 5968547 (1999-10-01), Reder et al.
patent: WO 99/38869 (1999-08-01), None
J. Marton et al. “Herstellung von 6,14-Ethenomorphinan-Derivaten” Monatshefte fur Chemie 125 (11), 1229-1239 (1994).

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