Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-05-22
1997-06-17
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514339, 546256, 5462774, 546273, 548495, A61K 31405, A61K 3144, A61K 31395, C07D20918, C07D40112, C07D20904
Patent
active
056397801
ABSTRACT:
The invention encompasses the novel compound of Formula I useful in the treatment of cyclooxygenase-2 mediated diseases. ##STR1## The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.
REFERENCES:
patent: 3161654 (1964-12-01), Shen
patent: 3196162 (1965-07-01), Sarett et al.
patent: 3242163 (1966-03-01), Sarett et al.
patent: 3654349 (1972-04-01), Shen et al.
patent: 3725548 (1973-04-01), Shen et al.
Chem. Abstracts, vol. 61, p. 4320 (a) (1964) "Resolution of Substituted Indoles" 1-p-chlorobenzyl-2-methyl-5-methoxy-3-indolyl)propionic acid.
Black Cameron
Ducharme Yves
Gauthier Jacques-Yves
Guay Daniel
Hamel Pierre
Merck Frosst Canada Inc.
Panzer Curtis C.
Rose David L.
Springer David B.
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