N-Benzyl anthracyclines

Details N-Benzyl anthracyclines N-Benzyl anthracyclines

1979-08-24

1981-02-10

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, C07H 1524

Patent

active

042503035

ABSTRACT:
N-Benzyl and N,N-dibenzyl derivatives of the anthracycline compounds adriamycin and daunomycin, said derivatives having anticancer properties and being active against leukemia P-388 in mice, for example. The N,N-dibenzyl derivatives have the unique quality of exhibiting a loss of DNA-binding properties.

REFERENCES:
patent: 3803124 (1974-04-01), Arcamone et al.

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