Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1978-10-02
1979-12-04
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
536 17A, A61K 3171, C07H 1524
Patent
active
041772644
ABSTRACT:
N-Benzyl and N,N-dibenzyl derivatives of the anthracycline compounds adriamycin and daunomycin, said derivatives having anticancer properties and being active against leukemia P-388 in mice, for example. The N,N-dibenzyl derivatives have the unique quality of exhibiting a loss of DNA-binding properties.
REFERENCES:
patent: 3803124 (1974-04-01), Arcamone et al.
Henry David W.
Smith Thomas H.
Wu Helen Y.
Brown Johnnie R.
De Witt Donovan J.
SRI - International
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