N-Benzhydryloxyethyl-N-phenylpropyl-piperazines

Details N-Benzhydryloxyethyl-N-phenylpropyl-piperazines N-Benzhydryloxyethyl-N-phenylpropyl-piperazines

1977-12-14

1980-05-13

Tovar, Jose

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544397, A61K 31495, C07D29508

Patent

active

042028965

ABSTRACT:
Piperazine derivatives of the general formula ##STR1## wherein R.sub.1 -R.sub.9 are the same or different and each represents a hydrogen or halogen atom or a lower alkyl or lower alkoxy group, n is 2 or 3 and X represents a group (CH.sub.2).sub.m (in which m is 1, 2, 3 or 4) or a group --CH.sub.2 --CH.dbd.CH--, having methylene linked to the piperazine group, and acid addition and quaternary ammonium salts thereof, are described.
The compounds exhibit a strong specific dopaminergic activity.
Also described are methods for their preparation and use as therapeutic agents in the form of therapeutic compositions.

REFERENCES:
patent: 2953568 (1960-09-01), Werner
patent: 3238209 (1966-03-01), Nakanishi et al.
patent: 3652568 (1972-03-01), Winter et al.

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