N-(arylthioalkyl)-N'-(aminoalkyl)ureas

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2605011, 26050117, 26050118, 514255, 514232, 514331, 514428, 514471, 514522, 514586, 514595, 514212, 544159, 544160, 544400, 546205, 546233, 549479, 564 26, 564 27, 564 47, 564 48, 564 52, 564 53, 564 54, 564 56, 558412, 558413, 558417, C07C12717, C07C15707, A61K 3107

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045979022

ABSTRACT:
N-(arylthioalkyl)-N'-(aminoalkyl)ureas and thioureas and oxidation derivatives having the formula ##STR1## wherein B is thio, sulfinyl or sulfonyl; R.sup.1 and R.sup.2 are hydrogen, loweralkyl, cycloalkyl, 2-furanyl, phenyl, substituted phenyl or phenyl-loweralkyl and R.sup.3 and R.sup.4 are hydrogen, loweralkyl, phenyl or phenyl-loweralkyl wherein phenyl is optionally substituted, or R.sup.3 and R.sup.4 taken with the adjacent nitrogen form a heterocyclic residue.

REFERENCES:
patent: 2344934 (1944-03-01), West
patent: 4279911 (1981-07-01), Martin-Smith et al.
patent: 4500529 (1985-02-01), Shanklin, Jr. et al.
patent: 4558155 (1985-12-01), Shanklin, Jr. et al.
Koelzer et al, Arzneim. Forsch. 9, pp. 113-120 (1959).

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