Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1999-04-07
2000-11-21
Higel, Floyd D.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
514394, 514415, 514418, 5483057, 5483067, 548457, 548462, C07D23504, C07D23522, C07D20948, A61K 314184, A61K 31404, A61N 2524
Patent
active
061505331
ABSTRACT:
Compounds effective in treating disorders of the serotonin-affected neurological systems are provided, such compounds having the following formula: ##STR1## wherein: R.sub.1 is hydrogen, lower alkyl, phenyl, or substituted phenyl;
REFERENCES:
patent: 3371098 (1968-02-01), Kralt et al.
patent: 4873346 (1989-10-01), Anderson
patent: 4954502 (1990-09-01), Smith et al.
patent: 5338756 (1994-08-01), Fortin et al.
patent: 5436264 (1995-07-01), Pfister et al.
patent: 5541204 (1996-07-01), Sher et al.
patent: 5693652 (1997-12-01), Takase et al.
patent: 5885987 (1999-03-01), Timmerman et al.
Artigas et al., Trends Neurosci., 19:378-383 (1996).
Dirk, R. et al: "Synthesis of (11C0 RPR-72840A and Its Evaluation as a Radioligand for the Serotonin Reuptake Site In Positron Emission Tomography", Chemical Abstract & Indexes, 126(20) (1997). Abstract.
Nelson, D. L., Pharmacology Biochemistry & Behavior, 40(4):1041-51 (1991).
Sleight, A.J. et al., "Identification of 5-hydroxytryptamine 1A Receptor Agents Using A Composite Pharmacophore Analysis and Chemical Database Screening", Naunyn-Schmiedeberg's archives of Pharmacology, 343:109-16 (1991).
Glennon, R. A., "Concepts for the design of %-HT1A Serotonin agonists and antagonists", Drug Development Research, 26(3):251-274 (1992).
Cliffe, I. A. et al., Drugs of the Future, 18(7):631-42 (1993).
Mewshaw Richard E.
Nelson James A.
American Home Products Corp.
Higel Floyd D.
Nagy Michael R.
LandOfFree
N-aryloxyethyl-indoly-alkylamines for the treatment of depressio does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with N-aryloxyethyl-indoly-alkylamines for the treatment of depressio, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-aryloxyethyl-indoly-alkylamines for the treatment of depressio will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1258809