Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-04-20
1991-10-01
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514262, 514265, 514266, 514326, 514316, 514320, 514321, 514322, 544266, 544211, 544216, 544217, 544285, 544286, 544284, 544289, 544290, 544291, 544292, 544293, 546196, 546198, 546199, 546201, 546202, 546208, 546212, 546213, A61K 31505, A61K 3152, C07D47502, C07D23972
Patent
active
050534114
ABSTRACT:
This invention pertains to novel substituted N-aryl-N-[4-(1-heterocyclicalkyl)piperidinyl]amides useful as analgesics, and methods of administering analgesia, which comprises the systemic administration to mammals of such compounds, and pharmaceutical compositions containing such compounds, wherein the novel compounds have the general formula: ##STR1## including optically active isomeric forms, and the pharmaceutically acceptable acid addition salts thereof, wherein R, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are defined in the disclosure.
REFERENCES:
patent: 4584303 (1986-04-01), Huang et al.
patent: 4791120 (1988-12-01), Lin et al.
Colapret et al., J. Med. Chem., vol. 32, 968-974 (1989).
Bagley Jerome R.
Huang Bao-Shan
Lalinde Nhora L.
Spencer H. Kenneth
Anaquest, Inc.
Cassett Larry R.
Shah Mukund J.
Swope R. Hain
Venkat Jyothsna
LandOfFree
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