N- And carboxyl derivatives of thienamycin

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...

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Details

2602452T, 424251, 424263, 424269, 424270, 424272, 424273R, 546272, 544316, C07D48704, A61K 3140

Patent

active

043978614

ABSTRACT:
Disclosed are N-acyl and carboxyl derivatives of the antibiotic thienamycin, which has the following structure: ##STR1## Such derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such derivatives, pharmaceutical compositions comprising such derivatives and methods of treatment comprising administering such derivatives and compositions when an antibiotic effect is indicated.

REFERENCES:
patent: 4162324 (1979-07-01), Cassidy et al.
patent: 4165379 (1979-08-01), Kahan et al.

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