N-Aminoalkyl-2-anthraquinonecarboxamides; new dopamine receptor

Details N-Aminoalkyl-2-anthraquinonecarboxamides; new dopamine receptor N-Aminoalkyl-2-anthraquinonecarboxamides; new dopamine receptor

1996-04-18

1997-12-30

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D24104, C07D29500

Patent

active

057032378

ABSTRACT:
Disclosed are compounds of the formula: ##STR1## or the pharmaceutically acceptable acid addition salts thereof wherein: R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, and R.sub.7 are the same or different and represent hydrogen, halogen, alkyl, alkoxy, hydroxy, cyano, nitro, trifluoromethyl, trifluoromethoxy; --O.sub.2 CR', --NHCOR', --COR', --SO.sub.m R', where R' is C.sub.1 -C.sub.6 alkyl and wherein m is 0, 1 or 2; or

REFERENCES:
patent: 3622580 (1971-11-01), Hromatka
patent: 5380725 (1995-01-01), Abou-Gharbia et al.
patent: 5395865 (1995-03-01), Glase et al.
Murray et al., (1995), "A Novel Series of Arylpiperazines with High Affinity and Selectivity for the Dopamine D.sub.3 Receptor, " Bioorg, Med. Chem. Let.,vol. 5, no. 3, pp. 219-222.

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