N'-(Aminoacylaminophenyl) acetamidines

Details N'-(Aminoacylaminophenyl) acetamidines N'-(Aminoacylaminophenyl) acetamidines

1974-09-13

1977-12-20

Killos, Paul J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

560 32, 560163, 260239BF, 260519, 260518A, 260268R, 26029376, 2602949, 260295R, 26032615, 2603262, 2603264, 26032647, 2603472, 2603473, 26034673, 260463, 260518R, 260558A, 260561S, 260562N, 544165, 544159, 544163, 544143, 548336, 548342, C07D29500

Patent

active

040642704

ABSTRACT:
A new class of N'-(aminoacylaminophenyl) acetamidines: ##STR1## in which R.sup.1 and R.sup.2 are the same or different and represent hydrogen, alkyl, aryl or the substituted derivatives thereof or, together with the nitrogen atom to which they are attached, an heterocyclic ring; and R.sup.3 is hydrogen, alkyl, aryl, aralkyl, or a heterocyclic moiety including the substituted derivatives thereof. The products have utility as anthelmintics.
The products are obtained by treating a suitable amino-acid or a carbonyl-activated amino-acid, with the appropriate N'-(4-aminophenyl)-N,N-dimethylacetamidine. In addition, the products are obtained by treating a suitable N'-(haloacylaminophenylacetamidine with an appropriate amine.

REFERENCES:
patent: 3336384 (1967-08-01), Gee
patent: 3729470 (1973-04-01), Vaille

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