N-Amino indole derivatives having pharmacological activity

Details N-Amino indole derivatives having pharmacological activity N-Amino indole derivatives having pharmacological activity

1978-05-05

1980-05-27

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603261, 26032613D, 424269, 424273R, 424273B, 424273N, 424274, 546273, 548257, 548260, 548329, 548371, C07D20944, C07D20908, C07D24918, C07D23522

Patent

active

042049989

ABSTRACT:
Novel hydrazines are disclosed in which one of the nitrogen atoms forms a ring member of the five membered ring of a [4.3.0] heterobicyclic compound which may be substituted elsewhere in the ring system. Characteristic ring systems described include indole and benztriazole ring systems. The compounds possess anti-depressant properties as well as anti-microbial, in particular fungistatic and bacteriostatic, properties.

REFERENCES:
Meyer, J. Chem. Soc. 1965, 3451-3454.
Arguzov, J. Gen. Chem. USSR (1957) 9, 2341-2354.
Schatz et al., Chem. Abs. 84, 30886 (1975).
Jones, J.C.S. Perkins I, 2728-2731 (1972).
Somei et al., I. Tet Letters 461-462 (1974).
Somei et al. II Tet Letters 3605-3608 (1974).

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