[N-alpha-acyl,8-glycine, des-19-leucine]-calcitonin

Details [N-alpha-acyl,8-glycine, des-19-leucine]-calcitonin [N-alpha-acyl,8-glycine, des-19-leucine]-calcitonin

1987-05-26

1988-08-16

Phillips, Delbert R.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Calcitonin; related peptides

C07K 736

Patent

active

047645890

ABSTRACT:
New hypocalcaemic peptides are disclosed of the formula ##STR1## wherein X represents acyl groups for the acylation of the N alpha-amino group and the radicals of carboxylic acids especially of formic, acetic, propionic, buteric, valeric, hexanoic, heptanoic, octanoic, and nonanoic acids along with all their respective isomers. We also wish to include L-lactic acid along with the half amides of malonic, succinic, glutaric and adipic acids.

REFERENCES:
patent: 4632978 (1986-12-01), Seyler et al.
patent: 4639511 (1987-01-01), Orlowski et al.

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