N.alpha.-(3-Cyanopropanoyl)-aminocarboxylic acid derivatives and

Details N.alpha.-(3-Cyanopropanoyl)-aminocarboxylic acid derivatives and N.alpha.-(3-Cyanopropanoyl)-aminocarboxylic acid derivatives and

1983-10-28

1985-04-16

Brust, Joseph Paul

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

260239A, 260463, 548533, 548342, C07D20504, C07D20712, C07D21140

Patent

active

045117195

ABSTRACT:
There are prepared specific .alpha.-aminocarboxylic acids or their methyl, ethyl, or benzyl esters in which the .alpha.-amino group is substituted by a 3-cyanopropanoyl group. The compounds are useful for producing the corresponding derivatives of 4-aminobutyramide ("Gabamide") by catalytic hydrogenation of the cyano group.

REFERENCES:
patent: 4091024 (1978-05-01), Ondetti
patent: 4332725 (1982-06-01), Fischer et al.
patent: 4426532 (1984-01-01), Kleemann et al.
Bey et al.; C. A., 95: 98321q, (1981), vol. 95.

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