N-alkylenepiperidino compounds, their enantiomers and pharmaceut

Details N-alkylenepiperidino compounds, their enantiomers and pharmaceut N-alkylenepiperidino compounds, their enantiomers and pharmaceut

1992-05-04

1995-05-02

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514319, 514327, 514329, 544130, 546205, 546217, 546223, 546224, A61K 31445, C07D41312, C07D40112, C07D21158

Patent

active

054119715

ABSTRACT:
The invention relates to N-alkylenepiperidino compounds of formula ##STR1## as well as their enantiomers, and pharmaceutical compositions containing them that are useful as antagonists of neurokinin receptors in the treatment of substance P- and/or neurokinin-independent pathologies.

REFERENCES:
patent: 3998834 (1976-12-01), Janssen et al.
patent: 4134982 (1979-01-01), Wise et al.
patent: 4179569 (1979-12-01), Janssen et al.
patent: 4246267 (1981-01-01), Vincent et al.

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