N-adamantlmethyl derivatives and intermediates as...

Details N-adamantlmethyl derivatives and intermediates as... N-adamantlmethyl derivatives and intermediates as...

2006-10-31

2006-10-31

Wilson, James O. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S352000, C514S353000, C514S357000, C546S296000, C546S297000, C546S300000, C546S301000

Reexamination Certificate

active

07129246

ABSTRACT:
The invention provides compounds of general formula (I) in which m, A, R1and Ar have the meanings defined in the specification; a process for, and intermediates used in, their preparation; pharmaceutical compositions containing them; a process for preparing the pharmaceutical compositions; and their use in therapy.

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Costakis et al., “Synthesis of Some Adamantane Derivatives of 2-Aminobenzothiazoles”,Journal of Medicinal Chemistry14(12):1222-1223 (1971).
Ho et al., “Synthesis of a Peptidomimetic Tricyclic Tetrahydrobenzo[ij] quinoline as a VLA-4 Antagonist”,J. Org. Chem. 65:6743-6748, p. 6745, scheme 5, (27) (2000).
STN International, File REGISTRY, see RN 405068-97-5, 405070-41-9, 405076-22-4, Apr. 14, 2002.
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STN International, File CHEMCATS, Accession No. 2001:48444, May 14, 2001, NS18552, 2-Quinolinecarboxamide, N-(tricycle[3.3.1.13,7]dec-1-ylmethyl), CAS Registry No. 313688-07-2.
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