Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Reexamination Certificate
2006-05-30
2006-05-30
Kumar, Shailendra (Department: 1621)
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
C564S143000, C564S158000, C562S455000, C558S392000, C514S520000, C514S521000, C514S535000, C514S616000
Reexamination Certificate
active
07053245
ABSTRACT:
This invention relates to N-acylamino aryl derivatives of the formulawhereR1, R21, R22, R23, R24, R3, R4, R5, R6, R7, R8, R, andn are as defined herein and whereX is —CHRO, —OCHR—, —CH2S—, —SCH2—, —CH2CH2—, —CH═CH— or —C≡C—.The compounds of the invention are selective monoamine oxidase B inhibitors, and they are therefore useful in the treatment of diseases mediated by monoamine oxidase B, for example, for the treatment of Alzheimer's disease or senile dementia.
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Abstract corresponding to JP 5262718.
Jolidon Synese
Rodriguez Sarmiento Rosa Maria
Thomas Andrew William
Wyler Rene
Hoffmann-La Roche Inc.
Johnston George W.
Kumar Shailendra
Prior Kimberly J.
Rocha-Tramaloni Patricia S.
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