N-acylamino benzyl ether derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing

Reexamination Certificate

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C564S143000, C564S158000, C562S455000, C558S392000, C514S520000, C514S521000, C514S535000, C514S616000

Reexamination Certificate

active

07053245

ABSTRACT:
This invention relates to N-acylamino aryl derivatives of the formulawhereR1, R21, R22, R23, R24, R3, R4, R5, R6, R7, R8, R, andn are as defined herein and whereX is —CHRO, —OCHR—, —CH2S—, —SCH2—, —CH2CH2—, —CH═CH— or —C≡C—.The compounds of the invention are selective monoamine oxidase B inhibitors, and they are therefore useful in the treatment of diseases mediated by monoamine oxidase B, for example, for the treatment of Alzheimer's disease or senile dementia.

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Abstract corresponding to JP 5262718.

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