N-Acetylneuraminic acid derivatives and the preparation thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

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536 24, C07H 1700

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active

044476000

ABSTRACT:
Nucleoside or glucose derivatives of N-acetylneuraminic acids are provided, which have immunological activity, are clinically useful, as an immuno suppressive, in particular to treat autoimmune disease such as collagenosis disease without causing any serious side-effects and may be prepared by subjecting a halide of N-acetylneuraminate derivative together with a nucleoside or a glucose to Koenigs-Knorr reaction.

REFERENCES:
patent: 3308117 (1967-03-01), Kelly et al.
patent: 4202968 (1980-05-01), Tamura et al.

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