N-acetylmannosamine dehydrogenase gene and novel recombinant DNA

Details N-acetylmannosamine dehydrogenase gene and novel recombinant DNA N-acetylmannosamine dehydrogenase gene and novel recombinant DNA

1990-12-27

1999-08-24

Wax, Robert A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

435 691, 43525233, 4353201, 536 237, 935 14, 935 29, 935 72, 935 73, C12N 904, C12N 1553, C12N 1570

Patent

active

059424273

ABSTRACT:
N-acetylmannosamine dehydrogenase gene derived from a microorganism belonging to the genus Flavobacterium, e.g., Flavobacterium sp. No. 141-8 strain and defined by a specific restriction enzyme map which encodes 271 amino acid sequence. Using the recombinant DNA, N-acetylmannosamine dehydrogenase can be produced in a simpler manner in an industrial scale. The enzyme is useful for quantitative determination of sialic acid.

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