N-acetylglucosaminyltransferase V proteins and coding sequences

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Transferase other than ribonuclease

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435325, 4352523, 43525233, 4353201, 536 232, C12N 1554, C12N 1574, C12N 1585

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active

060157011

ABSTRACT:
The present invention provides substantially purified UDP-N-acetylglucosamine: .alpha.-6-D-mannoside .beta.-1,6-N-acetylglucosaminyl transferase (GlcNAc T-V; EC 2.4.1.155) proteins and antibodies which specifically bind GlcNAc T-V. The present invention also provides polynucleotide sequences and oligonucleotide probes capable of specifically hybridizing to nucleic acid sequences which encode GlcNAc T-V, and cDNA and genomic clones encoding GlcNAc T-V, as well as nucleotide sequences encoding GlcNAc T-V, as specifically exemplified by GlcNAc T-V coding sequences from rat, hamster, mouse and human.

REFERENCES:
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