N-acetylglucosamine 2-epimerase and DNA encoding the same

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Isomerase

Reexamination Certificate

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C435S252330, C435S094000, C435S320100, C536S023200

Reexamination Certificate

active

06946281

ABSTRACT:
The present invention provides a novel protein having N-acetylglucosamine 2-epimerase activity; a DNA encoding the protein; a recombinant vector containing the DNA; a transformant obtainable by introducing the recombinant vector into a host cell; and a process for producing the protein or N-acetylmannosamine using the transformant.

REFERENCES:
patent: 0 708 177 (1996-04-01), None
Kaneko, et al., “Sequence Analysis of the Genome of the Unicellular . . . ”, DNA Research, vol. 3 (1996), pp. 109-136.
Maru, et al., “Molecular Cloning and Identification of N-Acyl-D-glucosamine . . . ”, The Journal of Biochemical Chemistry, vol. 271, No. 27 (1996), pp. 16294-16299.
Takahashi, et al., “Human Renin-Binding Protein Is the Enzyme . . . ”, J. Biochem., vol. 125 (1999), pp. 348-353.
Maru, et al., “Simple and Large-scale production of N-acetylneuraminic . . . ”, Carbohydrate Research, vol. 306 (1998), pp. 575-578.
Nakamura, et al., “CyanoBase, a www database containing . . . ”, Nucleic Acids Research, 1998, vol. 26 No. 1 (1998), pp. 63-67.
Kaneko, et al., (1996) Accession No. P74124.

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