(N-Acetyl)-Pro-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt and inte

Details (N-Acetyl)-Pro-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt and inte (N-Acetyl)-Pro-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt and inte

1974-11-14

1976-01-20

Gotts, Lewis

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424177, C07C10352, A61K 3700

Patent

active

039337820

ABSTRACT:
(N-Acetyl)-Pro-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt, is described as well as its synthesis by solid phase techniques and novel intermediates formed by such synthesis. The novel non-apeptide exhibits and anti-ovulatory activity in mammals.

REFERENCES:
fujino et al.: Biochem. Biophys, Res. Comm., 57, 1248-1256 (1974).
Coy et al.: Biochem. Biophys. Res. Comm., 57, 335-340 (1974).
Fujino et al.: Biochem. Biophys. Res. Comm., 49, 863-869 (1972).

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