Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1986-11-25
1988-03-29
Moyer, Donald B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
514618, 514866, 514884, 562427, 564162, A61K 3119, A61K 31165, C07C14714
Patent
active
047344350
ABSTRACT:
Disclosed herein are N-[[6-methoxy-5-(trifluoromethyl)-1-naphthalenyl]-thioxomethyl]-N-methylgl ycine S-oxide (tolrestat S-oxide) and the amide thereof and methods of their preparation. The S-oxides are new aldose reductase inhibitors useful for the treatment of prevention of diabetic complications.
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patent: 4439617 (1984-03-01), Sestanj
patent: 4447452 (1984-05-01), Sestanj
patent: 4568693 (1986-02-01), Sestanj et al.
patent: 4600724 (1986-07-01), Sestanj et al.
patent: 4604406 (1986-08-01), Bellini et al.
patent: 4672058 (1987-06-01), Bellini et al.
Ferdinandi Eckhardt S.
Malamas Michael S.
Sehgal Surendra N.
Sestanj Kazimir
American Home Products Corp.
Moyer Donald B.
Patton Walter
Scott Patricia M.
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