N[[5-(trifluoromethyl)-6-methoxy-1-naphthalenyl]-thioxomethyl]-N

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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558 8, 514563, 514588, 514599, 514866, 536 53, 536 552, 536 55, 564 44, 564 74, 564157, A61K 3170

Patent

active

046720588

ABSTRACT:
Disclosed herein are tolrestat amides and methods of preparation. The amides are new aldose reductase inhibitors useful for the treatment or prevention of diabetic complications.

REFERENCES:
patent: Re30563 (1981-03-01), Abdulla et al.
patent: 2135064 (1938-11-01), Whitmore et al.
patent: 3081302 (1963-03-01), Shapiro et al.
patent: 4282169 (1981-08-01), Rothgery et al.
patent: 4318924 (1982-03-01), Fest et al.
patent: 4439617 (1984-03-01), Sestanj

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