N-(5-thioxo-L-prolyl)-L-cysteine, derivatives thereof, processes

Details N-(5-thioxo-L-prolyl)-L-cysteine, derivatives thereof, processes N-(5-thioxo-L-prolyl)-L-cysteine, derivatives thereof, processes

1992-05-08

1993-10-19

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514423, 548527, 548537, 548519, A61K 3140, C07D20712, C07D40912, C07D40312

Patent

active

052545792

ABSTRACT:
N-(5-thioxo-L-prolyl)-L-cysteine and derivatives thereof, having interesting mucolytic-expectorant, antioxidant (radical-scavenger), antielastase, antiemphysema, immunostimulating and hepatoprotective activities and a low toxicity are described, as well as processes for the preparation thereof and pharmaceutical formulations for the use in therapy.

REFERENCES:
Inoue, et al., C.A. 91, (1979), 91:21136t.
Bjoerkman, et al., C.A., 94, (1981), 94:175517s.
Mueller, et al., C.A., 105, (1980), 105:79367t.
Benanti, et al., C.A., 112, (1990), 112:112100v.

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