N-[3-(p-f-benzoyl)-propyl]-N'-[2.(nitro,nitro-el, or methoxyphen

Details N-[3-(p-f-benzoyl)-propyl]-N'-[2.(nitro,nitro-el, or methoxyphen N-[3-(p-f-benzoyl)-propyl]-N'-[2.(nitro,nitro-el, or methoxyphen

1975-06-20

1976-07-13

Rollins, Alton D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424250, 424244, 260239BC, C07D29510

Patent

active

039693562

ABSTRACT:
1,4-diazacycloalkane derivatives of the formula ##SPC1##
Wherein
R is hydrogen, halogen, lower alkoxy, nitro or lower secondary amine,
R.sub.1 is lower alkoxyphenyl, nitrophenyl or trifluoromethylphenyl or wherein R.sub.1 is phenyl, that is disubstituted by two halogen, by two lower alkyl, by halogen and nitro, by halogen and lower alkyl, by halogen and lower alkoxy or by lower alkoxy and lower alkoyl, lower in these definitions meaning from 1 to 4 carbon atoms and wherein
n, n' and m are 2 or 3;
And pharmaceutically acceptable acid addition products of these compounds.
The compounds are sedatives with an analgesic and anti-histaminic effect and possess a low toxicity.

REFERENCES:
patent: 2695293 (1954-11-01), Swain
patent: 2695295 (1954-11-01), Swain
patent: 3000892 (1961-09-01), Janssen
patent: 3637704 (1972-01-01), Umemoto

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