N,3-disubstituted alaninamide derivatives

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514374, 514397, 514399, 514533, 548201, 548233, 548236, 548237, 548239, 5483345, 548495, 560 37, 560 38, 560 40, 562440, 562443, 562445, C07D277593, C07D26334, C07D23366, C07C 69612, A61K 31235, A61K 3141

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053128265

ABSTRACT:
Disclosed are a dicarboxylic acid compound represented by the formula (I): ##STR1## wherein R represents hydrogen atom, a lower alkyl group, phenyl group or hydroxyl group; R.sup.1 represents a straight or branched alkyl group having 1 to 10 carbon atoms or a lower alkyl group substituted by a group selected from aryl group, a sulfur- or nitrogen-containing heterocyclic monocyclic group and a cycloalkyl group having 4 to 8 carbon atoms; R.sup.2 represents a substituted or unsubstituted aryl group, a cycloalkyl group having 4 to 8 carbon atoms or a sulfur-containing or nitrogen-containing heterocylcic group; X represents sulfur atom, oxygen atom or a substituted or unsubstituted imino group; Y.sup.1 represents imino group, oxygen atom or sulfur atom and Y.sup.2 represents nitrogen atom, or Y.sup.1 represents a vinylene group and Y.sup.2 represents a group: --CH.dbd.; m represents 0 to 3; and n represents 0 or 1, an ester thereof or pharmaceutically acceptable salts thereof, and a process for preparing the same.

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