N-(23-vincristinoyl) and N-(5'-noranhydro-23-vinblastinoyl) comp

Details N-(23-vincristinoyl) and N-(5'-noranhydro-23-vinblastinoyl) comp N-(23-vincristinoyl) and N-(5'-noranhydro-23-vinblastinoyl) comp

1990-08-01

1992-03-31

Rivers, Diana G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Phosphorus containing other than solely as part of an...

540478, A61K 31475, C07D51904, C07F 96561

Patent

active

051008815

ABSTRACT:
The invention relates to the compounds of general formula I: ##STR1## in which: R.sub.1 represents a hydrogen atom, a linear or branched alkyl radical containing from 1 to 6 carbon atoms, a linear or branched alkenyl radical containing from 2 to 6 carbon atoms, an arylalkyl radical having 7 to 10 carbon atoms and which can bear a halogen atom as a substituent on the aromatic ring, a hydroxyl radical or an alkyl or alkoxy radical each containing from 1 to 5 carbon atoms, a 2-indolylmethyl radical, a 4-imidazolylmethyl radical or an alkoxycarbonylmethyl radical containing from 3 to 11 carbon atoms,

REFERENCES:
patent: 3354163 (1967-11-01), Gorman
patent: 4210584 (1980-07-01), Paschal et al.
patent: 4279915 (1981-07-01), Jovanovics et al.
patent: 4307100 (1981-12-01), Langlois et al.
patent: 4522750 (1985-06-01), Ades et al.
patent: 4619935 (1986-10-01), Robinson
patent: 4923876 (1990-05-01), Francis et al.
patent: 4946833 (1990-08-01), Lavielle et al.

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