N-(2-Substituted-1-oxoalkyl)-2,3-dihydro-1H-indole-2-carboxylic

Details N-(2-Substituted-1-oxoalkyl)-2,3-dihydro-1H-indole-2-carboxylic N-(2-Substituted-1-oxoalkyl)-2,3-dihydro-1H-indole-2-carboxylic

1982-06-22

1984-06-12

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D20942

Patent

active

044542917

ABSTRACT:
Disclosed herein are 2,3-dihydro-1H-indole-2-carboxylic acids substituted on the nitrogen with 3-mercapto-2-alkyl-1-oxoalkyl, 3-phosphoryl-2-alkyl-1-oxopropyl, or 2-amino-2-alkyl-1-oxoalkyl derivatives which act as inhibitors of angiotensin converting enzyme and as antihypertensive agents. The compounds of the invention (excluding disclosed intermediates) have the general formula: ##STR1## wherein: n is 1 or 0;

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